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Description: p75NTR fragment; induces apoptosis
Alternative Names: Neurotrophin receptor (368-381) amide
Biological Activity for NTR 368
NTR 368 is a peptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.
Technical Data for NTR 368
| M. Wt | 1565.87 |
| Formula | C69H124N22O19 |
| Sequence |
ATLDALLAALRRIQ-amide (Modifications: Ala-1 = N-terminal Ac, Gln-14 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 197230-90-3 |
| PubChem ID | 90488737 |
| InChI Key | ZUALDXYFESKMAR-SMVIZIMZSA-N |
| Smiles | CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for NTR 368
References for NTR 368
References are publications that support the biological activity of the product.
Hileman et al (1997) A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 415 145 PMID: 9350985
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Keywords: NTR 368, NTR 368 supplier, p75NTR, fragment, induces, apoptosis, Neurotrophin, Receptors, p75, Trk, RTKs, Receptor, Tyrosine, Kinases, NTR368, receptor, (368-381), amide, 2087, Tocris Bioscience
Citations for NTR 368
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Currently there are no citations for NTR 368.
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