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Submit ReviewLeelamine hydrochloride
Description: CB1 agonist
Alternative Names: Lylamine hydrochloride,(+)-Dehydroabietylamine
Chemical Name: (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine hydrochloride
Purity: ≥98% (HPLC)
Biological Activity for Leelamine hydrochloride
Leelamine hydrochloride is a CB1 agonist. Displaces binding of [3H]-SR141716A with an IC50 value of 2.86 μM.
Technical Data for Leelamine hydrochloride
| M. Wt | 321.93 |
| Formula | C20H31N.HCl |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 16496-99-4 |
| PubChem ID | 16759156 |
| InChI Key | CVPQLGCAWUAYPF-WFBUOHSLSA-N |
| Smiles | NC[C@]1(C)CCC[C@@]3(C)[C@]([H])1CCC2=CC(C(C)C)=CC=C23.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Leelamine hydrochloride
References for Leelamine hydrochloride
References are publications that support the biological activity of the product.
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Keywords: Leelamine hydrochloride, Leelamine hydrochloride supplier, CB1, agonists, cannabinoids, Receptors, cb1r, Leelamide, Lylamine, hydrochloride, (+)-Dehydroabietylamine, 2139, Tocris Bioscience
1 Citation for Leelamine hydrochloride
Citations are publications that use Tocris products. Selected citations for Leelamine hydrochloride include:
Gowda et al (2014) Nanolipolee-007, a novel nanoparticle-based drug containing leelamine for the treatment of melanoma. Mol Cancer Ther 13 2328 PMID: 25082958
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.