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Submit ReviewGBLD 345
Description: High affinity benzodiazepine agonist
Chemical Name: 2-(4-Aminophenyl)-3-methoxy-6-(3-methoxyphenyl)-methylimidazo[1,2-b]pyridazine
Biological Activity for GBLD 345
A high affinity benzodiazepine agonist (IC50 against diazepam = 1 nM).
Technical Data for GBLD 345
| M. Wt | 375.43 |
| Formula | C21H21N5O2 |
| Storage | Store at RT |
| CAS Number | 122479-08-7 |
| Smiles | NC(C=C4)=CC=C4C2=C(OC)N(C(C=C3)=N2)N=C3NCC1=CC=CC(OC)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for GBLD 345
Certificate of Analysis is currently unavailable on-line.
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References for GBLD 345
References are publications that support the biological activity of the product.
Davies et al (1992) Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors. Biochem.Pharmacol. 44 1555 PMID: 1358075
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Keywords: GBLD 345, GBLD 345 supplier, High, affinity, benzodiazepine, agonists, GABAA, Receptors, GBLD345, 0770, Tocris Bioscience
Citations for GBLD 345
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Currently there are no citations for GBLD 345.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
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