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Submit ReviewSomatostatin 1-28
Description: sst agonist
Purity: ≥95% (HPLC)
Biological Activity for Somatostatin 1-28
Somatostatin 1-28 is a somatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin.
Technical Data for Somatostatin 1-28
| M. Wt | 3149 |
| Formula | C137H207N41O39S3 |
| Sequence |
SANSNPAMAPRERKAGCKNFFWKTFTSC (Modification: Disulfide bridge: 17-28) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 74315-46-1 |
| PubChem ID | 16133849 |
| InChI Key | GGYTXJNZMFRSLX-DFTNLTQTSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Somatostatin 1-28
| Solubility | Soluble to 0.50 mg/ml in water |
Product Datasheets for Somatostatin 1-28
References for Somatostatin 1-28
References are publications that support the biological activity of the product.
Panetta et al (1994) Molecular cloning, functional characterization and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28. Mol.Pharmacol. 45 417 PMID: 7908405
Patel et al (1994) Expression of multiple somatostatin receptor genes in AtT-20 cells. Evidence for a novel somatostatin-28 selective receptor subtype. J.Biol.Chem. 269 1506 PMID: 7904601
Shimokawa et al (1997) Effect of somatostatin-28 on GH response to GH-releasing hormone-impact of aging and lifelong dietary restriction. Neuroendocrinol. 65 369 PMID: 9158069
If you know of a relevant reference for Somatostatin 1-28, please let us know.
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Keywords: Somatostatin 1-28, Somatostatin 1-28 supplier, Somatostatin, receptor, agonist, sst, Receptors, Somatostatin1-28, 1165, Tocris Bioscience
Citations for Somatostatin 1-28
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Reviews for Somatostatin 1-28
Average Rating: 5 (Based on 1 Review.)
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Somatostatin's ability to treat endocrine tumours was studied..
By
Anonymous on 11/30/2019
Species: Human
Somatostatin's ability to treat endocrine tumours was studied.
Binding affinity was studied at different developmental stages.Somatostatin receptor manipulation was also done.
