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Submit Review[Lys8]-Vasopressin is an antidiuretic hormone found in pigs and some marsupial families. Induces contraction of the rabbit urinary bladder smooth muscle.
M. Wt | 1056.22 |
Formula | C46H65N13O12S2 |
Sequence |
CYFQNCPKG (Modifications: Disulfide bridge between 1 - 6, Gly-9 = C-terminal amide) |
Storage | Desiccate at -20°C |
CAS Number | 50-57-7 |
PubChem ID | 90488785 |
InChI Key | BJFIDCADFRDPIO-KQZFXNKUSA-N |
Smiles | NCCCC[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@H]1CSSC[C@@H](N)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Crankshaw (1989) [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. Eur.J.Pharmacol. 173 183 PMID: 2625135
Gorbulev et al (1993) Molecular cloning and functional characterization of V2 [8-lysine] vasopressin and oxyt. receptors from a pig kidney cell line. Eur.J.Biochem. 215 1 PMID: 8393786
Keywords: [Lys8]-Vasopressin, [Lys8]-Vasopressin supplier, Antidiuretic, hormone, V2, Receptors, V1, Vasopressin, LVP, 2934, Tocris Bioscience
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.