Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMDL 29,913
Description: Selective NK2 antagonist
Biological Activity for MDL 29,913
MDL 29,913 is a NK2 tachykinin receptor selective antagonist.
Technical Data for MDL 29,913
| M. Wt | 745 |
| Formula | C40H56N8O6 |
| Sequence |
QWFGLL (Modifications: Leu-5 - Leu-6 = Leu-CH2N(CH3)-Leu, Cyclized) |
| Storage | Desiccate at -20°C |
| CAS Number | 135721-56-1 |
| PubChem ID | 90479769 |
| InChI Key | HTXNHRVBQSWFDI-QEQIFPIFSA-N |
| Smiles | CC(C)C[C@@H]1NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC1C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MDL 29,913
References for MDL 29,913
References are publications that support the biological activity of the product.
Black et al (1992) Tachykinin receptors in rabbit airways - characterization by functional, autoradiographic and binding studies. Br.J.Pharmacol. 107 429 PMID: 1384914
Maggi et al (1993) MEN 10,573 and MEN 10,612, novel cyclic pseudopeptides which are potent tachykinin NK-2 receptor antagonists. Regul.Pept. 47 151 PMID: 8234901
View Related Products by Target
View Related Products by Product Action
Keywords: MDL 29,913, MDL 29,913 supplier, Selective, NK2, antagonists, Tachykinin, Receptors, Neurokinin, MDL29913, Receptor, 1194, Tocris Bioscience
1 Citation for MDL 29,913
Citations are publications that use Tocris products. Selected citations for MDL 29,913 include:
Wease and Davies (2005) Substance P selectively decreases paired pulse depression in the rat hippocampal slice. BMC Neurosci 6 66 PMID: 16305744
Reviews for MDL 29,913
There are currently no reviews for this product. Be the first to review MDL 29,913 and earn rewards!
Have you used MDL 29,913?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.