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Submit ReviewCarcinine ditrifluoroacetate
Discontinued Product
2211 has been discontinued.
View all Histamine H<sub>3</sub> Receptors products.
Description: Highly selective H3 antagonist
Chemical Name: 3-Amino-N-[2-(1H-imidazol-4-yl)ethyl]propanamide ditrifluoroacetate
Purity: ≥98% (HPLC)
Biological Activity for Carcinine ditrifluoroacetate
Carcinine ditrifluoroacetate is a highly selective H3 receptor antagonist (Ki values are 0.30, 365 and 3621 μM for H3, H2 and H1 receptors respectively). Acts as a natural antioxidant with hydroxyl radical scavenging and lipid peroxidase activities.
Technical Data for Carcinine ditrifluoroacetate
| M. Wt | 410.27 |
| Formula | C8H14N4O.2CF3CO2H |
| Storage | Desiccate at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 2109435-79-0 |
| PubChem ID | 121513843 |
| InChI Key | YLYHHFINLFZZKK-UHFFFAOYSA-N |
| Smiles | NCCC(NCCC1=CN=CN1)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Carcinine ditrifluoroacetate
References for Carcinine ditrifluoroacetate
References are publications that support the biological activity of the product.
Babizhayev et al (1994) L-Carnosine (β-alanyl-L-histidine) and carcinine (β-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities. Biochem.J. 304 509 PMID: 7998987
Chen et al (2004) Pharmacological effects of carcinine on histaminergic neurons in the brain. Br.J.Pharmacol. 143 573 PMID: 15466447
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Keywords: Carcinine ditrifluoroacetate, Carcinine ditrifluoroacetate supplier, Highly, selective, H3, antagonists, Histamine, Receptors, histaminergic, 2211, Tocris Bioscience
Citations for Carcinine ditrifluoroacetate
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Histamine Receptors Scientific Review
Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.
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