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Submit ReviewSomatostatin
Description: Influences growth hormone release
Purity: ≥95% (HPLC)
Biological Activity for Somatostatin
Somatostatin is an endogenous peptide; inhibits the release of growth hormone, insulin and glucagon. Inhibits voltage-dependent calcium channels.
Technical Data for Somatostatin
| M. Wt | 1637.88 |
| Formula | C76H104N18O19S2 |
| Sequence |
AGCKNFFWKTFTSC (Modification: Disulfide bridge: 3-14) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 51110-01-1 |
| PubChem ID | 16129706 |
| InChI Key | NHXLMOGPVYXJNR-ATOGVRKGSA-N |
| Smiles | [H]N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Somatostatin
| Solubility | Soluble to 0.30 mg/ml in water |
Product Datasheets for Somatostatin
References for Somatostatin
References are publications that support the biological activity of the product.
Alderton et al (1998) Differential effects of somatostatin and angiopeptin on cell proliferation. Br.J.Pharmacol. 124 323 PMID: 9641549
Dileepan et al (1985) Somatostatin: a metabolic regulator. Life Sci. 37 2335 PMID: 2867445
Ohmura et al (1990) Somatostatin decreases the calcium inward current in guinea-pig atria. Br.J.Pharmacol. 99 587 PMID: 1970502
If you know of a relevant reference for Somatostatin, please let us know.
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Keywords: Somatostatin, Somatostatin supplier, Influences, growth, hormone, release, sst, Receptors, Somatostatin, 1157, Tocris Bioscience
3 Citations for Somatostatin
Citations are publications that use Tocris products. Selected citations for Somatostatin include:
Kothegala et al (2023) Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes Int J Mol Sci 24 3449
Chiu et al (2013) Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501 52 PMID: 23965627
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
Do you know of a great paper that uses Somatostatin from Tocris? Please let us know.
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