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Description: Potent, specific ligand for mitochondrial DBI receptor
Chemical Name: N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide
Purity: ≥98%
Biological Activity for FGIN-1-43
Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).
Technical Data for FGIN-1-43
| M. Wt | 487.51 |
| Formula | C28H36Cl2N2O |
| Storage | Store at RT |
| Purity | ≥98% |
| CAS Number | 145040-29-5 |
| PubChem ID | 3995234 |
| InChI Key | XTZUPNNVXIMWAR-UHFFFAOYSA-N |
| Smiles | O=C(N(CCCCCC)CCCCCC)CC2=C(C3=CC=C(Cl)C=C3)NC1=CC=C(Cl)C=C12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for FGIN-1-43
References for FGIN-1-43
References are publications that support the biological activity of the product.
Kozikowski et al (1993) Chemistry, binding affinities, and behavioural properties of a new class of "antineophobic" mitochondrial DBI receptor (mDRC) ligands. J.Med.Chem. 36 2908 PMID: 8411007
Romeo et al (1992) 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J.Pharmacol.Exp.Ther. 262 971 PMID: 1326631
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Keywords: FGIN-1-43, FGIN-1-43 supplier, Potent, specific, ligand, mitochondrial, DBI, receptor, GABAA, Receptors, FGIN143, Translocator, Protein, 0659, Tocris Bioscience
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