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Submit ReviewHomoquinolinic acid
Description: Potent and selective NMDA agonist
Purity: ≥99% (HPLC)
Biological Activity for Homoquinolinic acid
Potent NMDA receptor agonist; subtype-selective.
Technical Data for Homoquinolinic acid
| M. Wt | 181.15 |
| Formula | C8H7NO4 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 490-75-5 |
| PubChem ID | 3080554 |
| InChI Key | HQPMJFFEXJELOQ-UHFFFAOYSA-N |
| Smiles | OC(=O)CC1=CC=CN=C1C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Homoquinolinic acid
References for Homoquinolinic acid
References are publications that support the biological activity of the product.
Olverman et al (1988) Structure/activity relations of NMDA receptor ligands as studied by their inhibition of [3H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691
Prado de Carvalho et al (1996) The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptors subunits. Neurochem.Int. 28 445 PMID: 8740453
Stone (1984) Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. Br.J.Pharmacol. 81 175 PMID: 6546701
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Keywords: Homoquinolinic acid, Homoquinolinic acid supplier, Selective, potent, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0197, Tocris Bioscience
Citations for Homoquinolinic acid
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Currently there are no citations for Homoquinolinic acid.
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