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Submit Review7-Hydroxy-PIPAT maleate
Description: D3 agonist (D3 > D2)
Alternative Names: 7-OH-PIPAT
Chemical Name: (RS)-trans-7-Hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin maleate
Purity: ≥98% (HPLC)
Biological Activity for 7-Hydroxy-PIPAT maleate
This ligand has uniquely high affinity and selectivity for the D3 receptor. 8-Hydroxy-PIPAT maleate (Cat. No. 0797) also available.
Licensing Information
Sold with the permission of the University of Pennsylvania
Technical Data for 7-Hydroxy-PIPAT maleate
| M. Wt | 487.33 |
| Formula | C16H22INO.C4H4O4 |
| Storage | Desiccate at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 200722-46-9 |
| PubChem ID | 24978534 |
| InChI Key | IQRDHLSQXOATHD-HBRCEPSSSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.CCCN(C\C=C\I)C1CCC2=CC=C(O)C=C2C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 7-Hydroxy-PIPAT maleate
References for 7-Hydroxy-PIPAT maleate
References are publications that support the biological activity of the product.
Chumpradit et al (1993) Synthesis and optical resolution of (R)- and (S)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 DA receptor ligand. J.Med.Chem. 36 4308 PMID: 8277513
Foulon et al (1993) Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-amino]tetralin (trans-7-OH-PIPAT): a new D3 DA receptor ligand. J.Med.Chem. 36 1499 PMID: 8098771
Kung et al (1993) In vitro binding of a novel DA D3 receptor ligand: [125I]-trans-7-OH-PIPAT. Eur.J.Pharmacol. 235 165 PMID: 8519278
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Keywords: 7-Hydroxy-PIPAT maleate, 7-Hydroxy-PIPAT maleate supplier, D3, agonists, Dopamine, Receptors, dopaminergic, 7-OH-PIPAT, 0719, Tocris Bioscience
Citations for 7-Hydroxy-PIPAT maleate
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