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Submit ReviewLocustatachykinin I is an insect tachykinin-related peptide (TRP) isolated from Locusta migratoria. Exhibits sequence homology with vertebrate tachykinins.
M. Wt | 938.05 |
Formula | C43H63N13O11 |
Sequence |
GPSGFYGVR (Modifications: Arg-9 = C-terminal amide) |
Storage | Desiccate at -20°C |
CAS Number | 126985-97-5 |
PubChem ID | 195503 |
InChI Key | QVHUTTNZGVKOKQ-LINCNNNZSA-N |
Smiles | [H]NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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References are publications that support the biological activity of the product.
Torfs et al (2000) Characterization of a receptor for insect tachykinin-like peptide agonists by functional expression in a stable Drosophila Schneider 2 cell line. J.Neurochem. 74 2182 PMID: 10800964
Isaac et al (2002) Inactivation of a tachykinin-like peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders. Peptides 23 725 PMID: 11897392
Schoofs et al (1990) Locustatachykinin I and II, two novel insect neuropeptides with homology to peptides of the vertebrate tachykinin family. FEB Lett. 261 397
Keywords: Locustatachykinin I, Locustatachykinin I supplier, Insect, tachykinin-related, peptide, TRP, Non-Selective, Neurokinin, Receptors, LocustatachykininI, Lom-TKI, Lom-TK, I, Other, Tachykinin, 2690, Tocris Bioscience
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.