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Description: Acylator of PCP and σ receptors
Chemical Name: 1-(1-(3-Isothiocyanato)phenyl)cyclohexylpiperidine
Biological Activity for Metaphit
Acylator of PCP and σ-receptors.
Technical Data for Metaphit
| M. Wt | 300.46 |
| Formula | C18H24N2S |
| Storage | Desiccate at -20°C |
| CAS Number | 96316-00-6 |
| PubChem ID | 114745 |
| InChI Key | FGSGBQAQSPSRJK-UHFFFAOYSA-N |
| Smiles | S=C=NC1=CC(=CC=C1)C1(CCCCC1)N1CCCCC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Metaphit
References for Metaphit
References are publications that support the biological activity of the product.
Contreras et al (1986) Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. J.Pharmacol.Exp.Ther. 238 1101 PMID: 3018219
Debler et al (1989) Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. Eur.J.Pharmacol. 165 155 PMID: 2548879
Rafferty et al (1985) A specific acylating agent for the [3H]-phencyclidine receptors in rat brain. FEBS Lett. 181 318 PMID: 2982662
Reith et al (1991) Effect of metaphit on DArgic neurotransmission in rat striatal slices: involvement of the DA transporter and voltage-dependent sodium channel. J.Pharmacol.Exp.Ther. 259 1188 PMID: 1662274
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Keywords: Metaphit, Metaphit supplier, Acylator, PCP, σ, sigma, receptors, Sigma-Related, 0568, Tocris Bioscience
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