Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewThrombin Receptor Agonist Peptide
Description: Causes platelet aggregation and secretion
Alternative Names: TRAP
Purity: ≥95% (HPLC)
Biological Activity for Thrombin Receptor Agonist Peptide
Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 μM) and secretion.
Technical Data for Thrombin Receptor Agonist Peptide
| M. Wt | 1739.95 |
| Formula | C81H118N20O23 |
| Sequence | SFLLRNPNDKYEPF |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 137339-65-2 |
| PubChem ID | 16131180 |
| InChI Key | OXHYRVSBKWIFES-WWSDOYNLSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Thrombin Receptor Agonist Peptide
| Solubility | Soluble to 0.90 mg/ml in water |
Product Datasheets for Thrombin Receptor Agonist Peptide
References for Thrombin Receptor Agonist Peptide
References are publications that support the biological activity of the product.
Huang et al (1991) 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 266 18435 PMID: 1655750
Vassallo et al (1992) Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 267 6081 PMID: 1313429
Vu et al (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64 1057 PMID: 1672265
If you know of a relevant reference for Thrombin Receptor Agonist Peptide, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Thrombin Receptor Agonist Peptide, Thrombin Receptor Agonist Peptide supplier, Causes, platelet, aggregation, secretion, PAR, Receptors, Protease-Activated, thrombin, receptor, agonists, TRAP, 1185, Tocris Bioscience
2 Citations for Thrombin Receptor Agonist Peptide
Citations are publications that use Tocris products. Selected citations for Thrombin Receptor Agonist Peptide include:
Tripathi et al (2014) Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci 55 3912 PMID: 24876278
White et al (2015) A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Endocrinol 194 142 PMID: 25429068
Do you know of a great paper that uses Thrombin Receptor Agonist Peptide from Tocris? Please let us know.
Reviews for Thrombin Receptor Agonist Peptide
There are currently no reviews for this product. Be the first to review Thrombin Receptor Agonist Peptide and earn rewards!
Have you used Thrombin Receptor Agonist Peptide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image