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Submit ReviewMRS 2219
Description: Potentiates P2X1-mediated responses
Chemical Name: 1,5-Dihydro-3-hydroxy-8-methyl[1,3,2]dioxaphosphepino[5,6-c]pyridin-9-ol-3-oxide
Purity: ≥99% (HPLC)
Biological Activity for MRS 2219
A selective potentiator of ATP-evoked responses at rat P2X1 receptors (EC50 = 5.9 μM).
Technical Data for MRS 2219
| M. Wt | 231.14 |
| Formula | C8H10NO5P |
| Storage | Desiccate at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 14141-47-0 |
| PubChem ID | 3960826 |
| InChI Key | KCAJHODRYGNBSX-UHFFFAOYSA-N |
| Smiles | OC1=C(C)N=CC(CO2)=C1COP2(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MRS 2219
References for MRS 2219
References are publications that support the biological activity of the product.
Jacobson et al (1998) A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonise activation of P2X1 receptors. J.Med.Chem. 41 2201 PMID: 9632352
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Keywords: MRS 2219, MRS 2219 supplier, Potentiates, P2X1-mediated, responses, P2X, Receptors, Purinergic, modulators, purinoceptors, MRS2219, 1203, Tocris Bioscience
Citations for MRS 2219
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Currently there are no citations for MRS 2219.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.