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Submit ReviewRosmarinic acid
Description: GPR35 agonist; anti-inflammatory, cytostatic and antiviral
Chemical Name: [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid
Purity: ≥99% (HPLC)
Biological Activity for Rosmarinic acid
Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.
Technical Data for Rosmarinic acid
| M. Wt | 360.32 |
| Formula | C18H16O8 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 20283-92-5 |
| PubChem ID | 5281792 |
| InChI Key | DOUMFZQKYFQNTF-WUTVXBCWSA-N |
| Smiles | O=C(/C=C/C2=CC(O)=C(O)C=C2)O[C@@H](C(O)=O)CC1=CC(O)=C(O)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Rosmarinic acid
References for Rosmarinic acid
References are publications that support the biological activity of the product.
Van Kessel et al (1986) Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes. Agents Actions. 17 375 PMID: 3962787
Bult et al (1985) Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. Br.J.Pharmacol. 84 317 PMID: 3838489
Rampart et al (1986) Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid. Biochem.Pharmacol. 35 1397 PMID: 3516156
Sahu et al (1999) Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b. Biochem.Pharmacol. 57 1439 PMID: 10353266
Deng et al (2012) Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2 373 PMID: 22523636
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Keywords: Rosmarinic acid, Rosmarinic acid supplier, Anti-inflammatory, cytostatic, antiviral, GPR35, agonists, agonism, Non-selective, Antivirals, 0630, Tocris Bioscience
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