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Submit ReviewSynthalin sulfate
Description: Non-competitive NMDA antagonist
Chemical Name: N,N'-1,10-Decanediylbisguanidine sulfate
Biological Activity for Synthalin sulfate
An effective non-competitive NMDA receptor antagonist in vivo and in vitro; may bind to more than one site, one of which is the polyamine site.
Technical Data for Synthalin sulfate
| M. Wt | 354.47 |
| Formula | C12H28N6.H2SO4 |
| Storage | Store at RT |
| CAS Number | 182285-12-7 |
| PubChem ID | 66977 |
| InChI Key | OZZMUVKANAPKGI-UHFFFAOYSA-N |
| Smiles | OS(O)(=O)=O.NC(=N)NCCCCCCCCCCNC(N)=N |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Synthalin sulfate
References for Synthalin sulfate
References are publications that support the biological activity of the product.
Reynolds et al (1991) 1,10-Bis(guanidino)decane inhibits N-MthD.-aspartate responses in vitro and in vivo. J.Pharmacol.Exp.Ther. 259 626 PMID: 1658306
Reynolds (1992) Interactions between zinc and spermidine on the N-MthD.-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentam. J.Pharmacol.Exp.Ther. 263 632 PMID: 1432693
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Keywords: Synthalin sulfate, Synthalin sulfate supplier, Non-competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0635, Tocris Bioscience
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