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Submit ReviewTropanyl-3,5-dimethylbenzoate is a 5-HT3 antagonist.
M. Wt | 273.37 |
Formula | C17H23NO2 |
Storage | Store at RT |
Purity | ≥99% |
CAS Number | 85181-40-4 |
PubChem ID | 2837530 |
InChI Key | HDDNYFLPWFSBLN-UHFFFAOYSA-N |
Smiles | CN1C2CCC1CC(C2)OC(=O)C1=CC(C)=CC(C)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Fozard and Gitto (1983) Selective blockade of 5-hydroxytryptamine neuronal receptors by benzoic acid esters of tropine. Br.J.Pharmacol. 80 511P
Keywords: Tropanyl-3,5-dimethylbenzoate, Tropanyl-3,5-dimethylbenzoate supplier, 5-HT3, antagonists, Serotonin, Receptors, 0641, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Tropanyl-3,5-dimethylbenzoate include:
Yang et al (2010) Activation of submucosal 5-HT(3) receptors elicits a somatostatin-dependent inhibition of ion secretion in rat colon. Br J Pharmacol 159 1623 PMID: 20233224
Dolma et al (2016) Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell 29 859 PMID: 27300435
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.