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Submit Review1-Deoxymannojirimycin hydrochloride
Description: α-Mannosidase I inhibitor
Chemical Name: (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
Biological Activity for 1-Deoxymannojirimycin hydrochloride
1-Deoxymannojirimycin hydrochloride is a selective inhibitor of α-mannosidase I.
Technical Data for 1-Deoxymannojirimycin hydrochloride
| M. Wt | 199.63 |
| Formula | C6H13NO4.HCl |
| Storage | Desiccate at RT |
| CAS Number | 73465-43-7 |
| PubChem ID | 11019872 |
| InChI Key | ZJIHMALTJRDNQI-MVNLRXSJSA-N |
| Smiles | Cl[H].OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 1-Deoxymannojirimycin hydrochloride
References for 1-Deoxymannojirimycin hydrochloride
References are publications that support the biological activity of the product.
Bischoff et al (1986) The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells. J.Biol.Chem. 261 4766 PMID: 2937779
Bischoff and Kornfeld (1984) The effect of 1-deoxymannojirimycin on rat liver α-mannosidases. Biochem.Biophys.Res.Commun. 125 324 PMID: 6239623
Fuhrmann et al (1984) Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides. Nature 307 755 PMID: 6230538
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Keywords: 1-Deoxymannojirimycin hydrochloride, 1-Deoxymannojirimycin hydrochloride supplier, α-mannosidase, alpha-mannosidase, I, inhibitors, inhibits, a-Mannosidase, Glycosylases, Carbohydrate, Metabolism, antibiotics, Antibiotics, 1259, Tocris Bioscience
1 Citation for 1-Deoxymannojirimycin hydrochloride
Citations are publications that use Tocris products. Selected citations for 1-Deoxymannojirimycin hydrochloride include:
Tareen et al (2014) Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells. Mol Ther 22 575 PMID: 24419083
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