Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewPD 173212
Description: Potent CaV2.2 blocker
Chemical Name: N-[[4-(1,1-Dimethylethyl)phenyl]methyl-N-methyl-L-leucyl-N-(1,1-dimethylethyl)-O-phenylmethyl)-L-tyrosinamide
Purity: ≥98% (HPLC)
Biological Activity for PD 173212
PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). Displays selectivity over K+, Na+ and L-type Ca2+ channels. Prevents tonic seizures in the audiogenic seizure model in vivo.
Technical Data for PD 173212
| M. Wt | 599.85 |
| Formula | C38H53N3O3 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 217171-01-2 |
| PubChem ID | 9916734 |
| InChI Key | GCDHMGROXQUFNR-HEVIKAOCSA-N |
| Smiles | CC(C)(C)C1=CC=C(CN(C)[C@H](C(N[C@H]([C@](NC(C)(C)C)=O)CC2=CC=C(OCC3=CC=CC=C3)C=C2)=O)CC(C)C)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for PD 173212
References for PD 173212
References are publications that support the biological activity of the product.
Hu et al (1999) Structure-activity relationships of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers. Bioorg.Med.Chem.Letts. 9 2151
View Related Products by Target
View Related Products by Product Action
Keywords: PD 173212, PD 173212 supplier, Potent, N-type, Ca2+, channel, blockers, Calcium, CaV, Channels, voltage-gated, voltage-dependent, PD173212, Cav2.x, 3552, Tocris Bioscience
Citations for PD 173212
Citations are publications that use Tocris products.
Currently there are no citations for PD 173212.
Reviews for PD 173212
There are currently no reviews for this product. Be the first to review PD 173212 and earn rewards!
Have you used PD 173212?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image