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Submit ReviewQX 222
Discontinued Product
1043 has been discontinued.
View all Voltage-gated Sodium (Na<sub>V</sub>) Channels products.
Description: Na+ channel blocker
Chemical Name: 2-[(2,6-Dimethylphenyl)amino]-N,N,N-trimethyl-2-oxoethaniminium chloride
Biological Activity for QX 222
QX 222 is a sodium channel blocker.
Technical Data for QX 222
| M. Wt | 256.77 |
| Formula | C13H21ClN2O |
| Storage | Desiccate at RT |
| CAS Number | 5369-00-6 |
| PubChem ID | 9795082 |
| InChI Key | WFKXSWWTOZBDME-UHFFFAOYSA-N |
| Smiles | [Cl-].CC1=CC=CC(C)=C1NC(=O)C[N+](C)(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for QX 222
References for QX 222
References are publications that support the biological activity of the product.
Cuevas and Adams (1994) Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. Br.J.Pharmacol. 11 663 PMID: 7517326
Hanck et al (1994) Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J.Gen.Physiol. 103 19 PMID: 8169596
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Keywords: QX 222, QX 222 supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, QX222, Voltage-gated, 1043, Tocris Bioscience
2 Citations for QX 222
Citations are publications that use Tocris products. Selected citations for QX 222 include:
Slesinger (2001) Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels. Biophys J 80 707 PMID: 11159438
Li et al (2005) Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother 49 388 PMID: 15616319
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