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SAMS Peptide

Cat. No. 1344 1 Citation Submit a Review Datasheet / COA / SDS

Discontinued Product

1344 has been discontinued.

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Description: AMP-activated protein kinase substrate
Datasheet
Citations (1)
Reviews
Pathways (1)
Biological Activity Technical Data Datasheets References

Biological Activity for SAMS Peptide

SAMS Peptide is a substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, it is more specific for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK.

Technical Data for SAMS Peptide

M. Wt 1779.15
Formula C74H131N29O18S2
Sequence HMRSAMSGLHLVKRR
Storage Desiccate at -20°C
CAS Number 125911-68-4
PubChem ID 71773161
InChI Key YJAHUEAICBOBTC-CSVPVIMBSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for SAMS Peptide

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References for SAMS Peptide

References are publications that support the biological activity of the product.

Carling et al (1989) Purification and characterization of the AMP-activated protein kinase. Eur.J.Biochem. 186 129 PMID: 2598924

Davies et al (1989) Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur.J.Biochem. 186 123 PMID: 2574667

Hardie et al (1998) The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu.Rev.Biochem 67 821 PMID: 9759505

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Keywords: SAMS Peptide, SAMS Peptide supplier, AMP-activated, protein, kinase, AMPK, Kinases, Enzyme, Substrates, Activators, /, 1344, Tocris Bioscience

1 Citation for SAMS Peptide

Citations are publications that use Tocris products. Selected citations for SAMS Peptide include:

Thelander et al (2004) Snf1-related protein kinase 1 is needed for growth in a normal day-night light cycle. EMBO J 23 1900 PMID: 15057278

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Pathways for SAMS Peptide

AMPK Signaling Pathway

AMPK Signaling Pathway

AMPK signaling pathway plays an important role in the cellular reponse to low levels of available ATP, often caused by stresses such as heat shock, ischemia or hypoxia.