Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewS26948
Description: Selective PPARγ agonist; antidiabetic agent
Chemical Name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioic acid dimethyl ester
Purity: ≥99% (HPLC)
Biological Activity for S26948
Selective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats.
Technical Data for S26948
| M. Wt | 519.57 |
| Formula | C28H25NO7S |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 353280-43-0 |
| PubChem ID | 9958279 |
| InChI Key | NSMJEHGOMXSLCW-UHFFFAOYSA-N |
| Smiles | O=C(C3=CC=CC=C3)C1=CC=C(N(CCOC4=CC=C(CC(C(OC)=O)C(OC)=O)C=C4)C(S2)=O)C2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for S26948
References for S26948
References are publications that support the biological activity of the product.
Carmona et al (2007) S 26948: a new specific peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects. Diabetes 56 2797 PMID: 17704298
Sohn et al (2009) S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic Ins sensitivity in 48 h lipid infused rats. Eur.J.Pharmacol. 608 104 PMID: 19250932
View Related Products by Product Action
Keywords: S26948, S26948 supplier, Peroxisome, Proliferator-activating, Receptors, PPARg, PPARγ, PPARgamma, agonists, antidiabetic, S26948, 3690, Tocris Bioscience
Citations for S26948
Citations are publications that use Tocris products.
Currently there are no citations for S26948.
Reviews for S26948
There are currently no reviews for this product. Be the first to review S26948 and earn rewards!
Have you used S26948?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image