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Submit ReviewTolterodine L-tartrate
Description: Potent, non-selective muscarinic receptor antagonist
Chemical Name: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol (2R,3R)-2,3-dihydroxybutanedioate
Purity: ≥99% (HPLC)
Biological Activity for Tolterodine L-tartrate
High affinity muscarinic receptor antagonist (Ki = 3.3 nM). Active at all muscarinic receptor subtypes (M1 - M5); exhibits a greater effect on the bladder than salivary glands in vivo.
Licensing Information
Sold for research purposes under agreement from Pfizer Inc.
Compound Libraries for Tolterodine L-tartrate
Tolterodine L-tartrate is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.
Technical Data for Tolterodine L-tartrate
| M. Wt | 475.57 |
| Formula | C22H31NO.C4H6O6 |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 124937-52-6 |
| PubChem ID | 443878 |
| InChI Key | TWHNMSJGYKMTRB-KXYUELECSA-N |
| Smiles | OC1=C([C@@H]([C@]2=CC=CC=C2)CCN(C(C)C)C(C)C)C=C(C)C=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tolterodine L-tartrate
References for Tolterodine L-tartrate
References are publications that support the biological activity of the product.
Nilvebrant et al (1997) Tolterodine - a new bladder-selective antimuscarinic agent. Eur.J.Pharmacol. 327 195 PMID: 9200560
Nilvebrant (2001) Clinical experiences with tolter. Life Sci. 68 2549 PMID: 11392625
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Citations for Tolterodine L-tartrate
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Currently there are no citations for Tolterodine L-tartrate.
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