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Submit ReviewTUG 424
Description: FFA1 (GPR40) agonist
Chemical Name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoic acid
Purity: ≥99% (HPLC)
Biological Activity for TUG 424
Agonist of the free fatty acid receptor FFA1 (GPR40) (EC50 = 32 nM). Enhances glucose-stimulated insulin secretion in INS-1E cells at 100 nM.
Licensing Information
Sold under license from the University of Southern Denmark.
Technical Data for TUG 424
| M. Wt | 264.32 |
| Formula | C18H16O2 |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 1082058-99-8 |
| Smiles | CC1=CC=CC=C1C#CC2=CC=C(CCC(O)=O)C=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for TUG 424
References for TUG 424
References are publications that support the biological activity of the product.
Christiansen et al (2008) Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA1/GPR40), a potential target for the treatment of type II diabetes. J.Med.Chem. 51 7061 PMID: 18947221
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Keywords: TUG 424, TUG 424 supplier, TUG424, free, fatty, acid, receptors, ffa1, GPR40, agonists, Free, Fatty, Acid, Receptors, 3795, Tocris Bioscience
Citations for TUG 424
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