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Submit ReviewCompstatin control peptide
Description: Control peptide for Compstatin (Cat. No. 2585)
Purity: ≥95% (HPLC)
Biological Activity for Compstatin control peptide
Compstatin control peptide is a control peptide for Compstatin, a complement inhibitor.
Active Analog also available.
Technical Data for Compstatin control peptide
| M. Wt | 1488.67 |
| Formula | C66H101N23O17 |
| Sequence |
IAVVQDWGHHRAT (Modifications: Thr-13 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 301544-78-5 |
| PubChem ID | 90488879 |
| InChI Key | SAJZITDYWAOPDD-LSPMIEDISA-N |
| Smiles | [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Compstatin control peptide
| Solubility | Soluble to 1 mg/ml in water |
Product Datasheets for Compstatin control peptide
References for Compstatin control peptide
References are publications that support the biological activity of the product.
Sahu et al (1996) Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J.Immunol. 157 884 PMID: 8752942
Fiane et al (1999) Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Xenotransplantation 6 52 PMID: 10355733
Mollnes et al (2002) Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100 1869 PMID: 12176911
If you know of a relevant reference for Compstatin control peptide, please let us know.
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Keywords: Compstatin control peptide, Compstatin control peptide supplier, C3-binding, protein, inhibits, inhibitors, complement, activation, Convertase, control, peptide, Complement, 3796, Tocris Bioscience
1 Citation for Compstatin control peptide
Citations are publications that use Tocris products. Selected citations for Compstatin control peptide include:
Yumi et al (2023) Complement dependent TNFα production in neutrophil-like HL60 cells. Biochem Biophys Rep 34 101465 PMID: 37125077
Do you know of a great paper that uses Compstatin control peptide from Tocris? Please let us know.
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