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Submit Review6,2',4'-Trimethoxyflavone is an aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.
M. Wt | 312.32 |
Formula | C18H16O5 |
Storage | Store at RT |
Purity | ≥97% (HPLC) |
CAS Number | 720675-74-1 |
PubChem ID | 688802 |
InChI Key | WUWFDVDASNSUKP-UHFFFAOYSA-N |
Smiles | O=C1C3=C(C=CC(OC)=C3)OC(C2=CC=C(OC)C=C2OC)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Murray et al (2010) Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. J.Pharmacol.Exp.Ther. 332 135 PMID: 19828881
Keywords: 6,2',4'-Trimethoxyflavone, 6,2',4'-Trimethoxyflavone supplier, aryl, hydrocarbon, receptors, antagonists, AHR, 6,2,4-Trimethoxyflavone, Aryl, Hydrocarbon, Receptors, 3859, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for 6,2',4'-Trimethoxyflavone include:
Gimenez-Gomez et al (2018) Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens. Neuropharmacology 135 581 PMID: 29705534
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