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Submit ReviewErcalcitriol
Description: Active metabolite of vitamin D2
Alternative Names: 1α,25-Dihydroxyvitamin D2
Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7α-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Purity: ≥95% (HPLC)
Biological Activity for Ercalcitriol
Active metabolite of vitamin D2. Exhibits equipotent antirachitic activity in rats as calcitriol (Cat. No. 2551).
Technical Data for Ercalcitriol
| M. Wt | 428.65 |
| Formula | C28H44O3 |
| Storage | Desiccate at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 60133-18-8 |
| PubChem ID | 9547243 |
| InChI Key | ZGLHBRQAEXKACO-XJRQOBMKSA-N |
| Smiles | C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](/C=C/[C@H](C)C(C)(O)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Ercalcitriol
References for Ercalcitriol
References are publications that support the biological activity of the product.
Rambeck et al (1984) Biological activity of 1 alpha,25-dihydroxyergocalciferol in rachitic chicks and in rats. Int.J.Vitamin.Nutr.Res. 54 135
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Keywords: Ercalcitriol, Ercalcitriol supplier, Vitamin, D, receptor, VDR, agonists, Receptors, VDR-like, 1a,25-DihydroxyvitaminD2, 1alpha,25-DihydroxyvitaminD2, 1α,25-DihydroxyvitaminD2, 1a,25-Dihydroxyvitamin, D2, 3970, Tocris Bioscience
1 Citation for Ercalcitriol
Citations are publications that use Tocris products. Selected citations for Ercalcitriol include:
Kim et al (2014) Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells. Sci Rep 77 73 PMID: 25237378
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