Nalmefene - d3

Discontinued Product

3971 has been discontinued.

View all Miscellaneous Opioids products.
Description: Deuterated nalmefene; opioid receptor antagonist
Chemical Name: (5α)-17-(d3-Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for Nalmefene - d3

Deuterated nalmefene.

Nalmefene also available.

Technical Data for Nalmefene - d3

M. Wt 342.45
Formula C21H22D3NO3
Storage Store at +4°C
Purity ≥98% (HPLC)
PubChem ID 71750904
InChI Key WJBLNOPPDWQMCH-TVFUAGGXSA-N
Smiles C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C([2H])([2H])C6([2H])CC6)CC4)[C@@](O)2CC3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Nalmefene - d3

References for Nalmefene - d3

References are publications that support the biological activity of the product.

Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678

Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980

Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022

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Keywords: Nalmefene - d3, Nalmefene - d3 supplier, opioid, receptors, antagonists, deuterated, 55096-26-9, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, 3971, Tocris Bioscience

Citations for Nalmefene - d3

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Currently there are no citations for Nalmefene - d3.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Peptides Involved in Appetite Modulation Scientific Review

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.