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MM-22

Cat. No. 4104 Submit a Review Datasheet / COA / SDS

Discontinued Product

4104 has been discontinued.

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Description: Biotinylated anandamide analog; blocks anandamide uptake
Chemical Name: (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[2-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Datasheets References

Biological Activity for MM-22

Biotinylated anandamide analog; acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide. Blocks anandamide uptake (IC50 = 0.5 μM in HaCaT cells); prevents interaction with FAAH, CB1 and TRPV1.

Licensing Information

Sold under licence from the University of Rome and the University of Teramo

Technical Data for MM-22

M. Wt 660.95
Formula C36H60N4O5S
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 956605-71-3
PubChem ID 17755658
InChI Key OWGIWGPEYRGLKI-CJBBQPGESA-N
Smiles O=C(NCCOCCOCCNC(CCCC[C@H]1[C@](NC(N2)=O)([H])[C@]2([H])CS1)=O)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for MM-22

References are publications that support the biological activity of the product.

Fezza et al (2008) Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation. J.Lipid.Res. 49 1216 PMID: 18316795

Oddi et al (2008) Evidence for the intracellular accumulation of anandamide in adiposomes. Cell Mol.Life Sci. 65 840 PMID: 18213445

Oddi et al (2009) Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. Chem.Biol. 16 624 PMID: 19481477

Oddi et al (2010) Pitfalls and solutions in assaying anandamide transport in cells. J.Lipid.Res. 51 2435 PMID: 20447929

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Keywords: MM-22, MM-22 supplier, MM22, b-AEA, anandamide, biotinylated, analogs, intracellular, accumulation, trafficking, probe, CB1, CB2, cannabinoid, receptors, Non-selective, Cannabinoids, TRPV, 4104, Tocris Bioscience

Citations for MM-22

Citations are publications that use Tocris products.

Currently there are no citations for MM-22.

Reviews for MM-22

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.