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Submit ReviewAlfacalcidol
Description: Prodrug of vitamin D3 (Cat. No. 4156)
Alternative Names: 1-Hydroxycholecalciferol
Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol
Purity: ≥97% (HPLC)
Biological Activity for Alfacalcidol
Alfacalcidol is a metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.
Technical Data for Alfacalcidol
| M. Wt | 400.64 |
| Formula | C27H44O2 |
| Storage | Store at -20°C |
| Purity | ≥97% (HPLC) |
| CAS Number | 41294-56-8 |
| PubChem ID | 5282181 |
| InChI Key | OFHCOWSQAMBJIW-AVJTYSNKSA-N |
| Smiles | C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Alfacalcidol
References for Alfacalcidol
References are publications that support the biological activity of the product.
Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770
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Keywords: Alfacalcidol, Alfacalcidol supplier, VDR, activators, vitamin, D3, analogue, analog, receptors, 1-Hydroxycholecalciferol, Vitamin, D, Receptors, 4159, Tocris Bioscience
Citations for Alfacalcidol
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