Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMoclobemide
Description: Reversible MAO-A inhibitor
Chemical Name: 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide
Purity: ≥99% (HPLC)
Biological Activity for Moclobemide
Moclobemide is a reversible monoamine oxidase A (MOA-A) inhibitor.
Compound Libraries for Moclobemide
Moclobemide is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.
Technical Data for Moclobemide
| M. Wt | 268.74 |
| Formula | C13H17ClN2O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 71320-77-9 |
| PubChem ID | 4235 |
| InChI Key | YHXISWVBGDMDLQ-UHFFFAOYSA-N |
| Smiles | O=C(NCCN2CCOCC2)C1=CC=C(Cl)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Moclobemide
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.87 | 100 | |
| ethanol | 26.87 | 100 |
Preparing Stock Solutions for Moclobemide
The following data is based on the product molecular weight 268.74. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.72 mL | 18.61 mL | 37.21 mL |
| 5 mM | 0.74 mL | 3.72 mL | 7.44 mL |
| 10 mM | 0.37 mL | 1.86 mL | 3.72 mL |
| 50 mM | 0.07 mL | 0.37 mL | 0.74 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets for Moclobemide
References for Moclobemide
References are publications that support the biological activity of the product.
Merck Index 12 6309
Burkard et al (1989) Pharmacological profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A. J.Pharmacol.Exp.Ther. 248 391 PMID: 2913284
Prada et al (1989) Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A. J.Pharmacol.Exp.Ther. 248 400 PMID: 2783611
If you know of a relevant reference for Moclobemide, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Moclobemide, Moclobemide supplier, reversible, monoamine, oxidase, a, moa-a, inhibitors, inhibits, Monoamine, Oxidase, Adrenergic, Related, Compounds, Dopaminergic-Related, 5-HT-Related, 5-HT3, Receptors, 4395, Tocris Bioscience
1 Citation for Moclobemide
Citations are publications that use Tocris products. Selected citations for Moclobemide include:
Ulferts et al (2016) Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. Antimicrob Agents Chemother 60 2627 PMID: 26856848
Do you know of a great paper that uses Moclobemide from Tocris? Please let us know.
Reviews for Moclobemide
There are currently no reviews for this product. Be the first to review Moclobemide and earn rewards!
Have you used Moclobemide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.