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Submit Review(±)-CPSI 1306
Description: Reported macrophage migration inhibitory factor (MIF) inhibitor
Chemical Name: 2-[3-(3-(2,4-Difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)ethanone
Purity: ≥98% (HPLC)
Biological Activity for (±)-CPSI 1306
(±)-CPSI 1306 is reported to be a macrophage inhibitory factor (MIF) inhibitor.
This product is racemic.
Compound Libraries for (±)-CPSI 1306
(±)-CPSI 1306 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.
Technical Data for (±)-CPSI 1306
| M. Wt | 310.3 |
| Formula | C15H16F2N2O3 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1309793-47-2 |
| PubChem ID | 59723793 |
| InChI Key | GUWOSEVHCSNYFK-UHFFFAOYSA-N |
| Smiles | FC(C=C2F)=CC=C2C1=NOC(CC(N3CCOCC3)=O)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (±)-CPSI 1306
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.03 | 100 | |
| ethanol | 3.1 | 10 |
Preparing Stock Solutions for (±)-CPSI 1306
The following data is based on the product molecular weight 310.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.22 mL | 16.11 mL | 32.23 mL |
| 5 mM | 0.64 mL | 3.22 mL | 6.45 mL |
| 10 mM | 0.32 mL | 1.61 mL | 3.22 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.64 mL |
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Product Datasheets for (±)-CPSI 1306
References for (±)-CPSI 1306
References are publications that support the biological activity of the product.
Kithcart et al (2010) A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J. 24 4459 PMID: 20624927
Sanchez-Zamora et al (2010) Macrophage migration inhibitory factor is a therapeutic target in treatment of non-Ins-dependent diabetes mellitus. FASEB J. 24 2583 PMID: 20203087
If you know of a relevant reference for (±)-CPSI 1306, please let us know.
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Citations for (±)-CPSI 1306
Citations are publications that use Tocris products.
Currently there are no citations for (±)-CPSI 1306. Do you know of a great paper that uses (±)-CPSI 1306 from Tocris? Please let us know.
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