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Description: Negative control of SGC 707 (Cat. No. 5367)
Chemical Name: N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
Purity: ≥98% (HPLC)
Biological Activity for XY1
XY1 is a negative control of SGC 707. Exhibits >3000-fold lower potency (IC50 >100 μM) compared to the active analog.
Active Analog also available.
Licensing Information
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC 707 probe summary on the SGC website.
Compound Libraries for XY1
XY1 is also offered as part of the Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.
Technical Data for XY1
| M. Wt | 297.35 |
| Formula | C17H19N3O2 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1624117-53-8 |
| PubChem ID | 78871801 |
| InChI Key | GSQHGSRPQHBTTP-UHFFFAOYSA-N |
| Smiles | O=C(NCC(N3CCCC3)=O)NC2=CC1=CC=CC=C1C=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for XY1
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.73 | 100 |
Preparing Stock Solutions for XY1
The following data is based on the product molecular weight 297.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.36 mL | 16.82 mL | 33.63 mL |
| 5 mM | 0.67 mL | 3.36 mL | 6.73 mL |
| 10 mM | 0.34 mL | 1.68 mL | 3.36 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.67 mL |
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Product Datasheets for XY1
References for XY1
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Keywords: XY1, XY1 supplier, Negative, controls, SGC, 707, allosteric, inhibitors, inhibits, protein, arginine, methyltransferases, 3, PRMT3, Protein, Arginine, Methyltransferases, 5450, Tocris Bioscience
Citations for XY1
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.