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Submit ReviewLatanoprost
Description: FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors
Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester
Purity: ≥97% (HPLC)
Biological Activity for Latanoprost
Latanoprost is a FP prostaglandin receptor agonist; displays greater selectivity than prostanglandin F2α (Cat. No. 4214). Exhibits agonist activity at EP1 and EP3 receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors.
Technical Data for Latanoprost
| M. Wt | 432.59 |
| Formula | C26H40O5 |
| Storage | Store at -20°C |
| Purity | ≥97% (HPLC) |
| CAS Number | 130209-82-4 |
| PubChem ID | 5311221 |
| InChI Key | GGXICVAJURFBLW-CEYXHVGTSA-N |
| Smiles | O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Latanoprost
References for Latanoprost
References are publications that support the biological activity of the product.
Stjernschantz (2001) From PGF2α-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture. Invest.Ophthalmol.Vis.Sci. 42 1134 PMID: 11328719
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Keywords: Latanoprost, Latanoprost supplier, Pfizer, latanoprost, prostaglandins, receptors, FP, agonists, EP1, EP3, Prostanoid, Receptors, 4757, Tocris Bioscience
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