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Submit ReviewLUF 6283
Discontinued Product
4881 has been discontinued.
View all Hydroxycarboxylic Acid Receptors products.
Description: HCA2 (GPR109A) partial agonist
Chemical Name: 5-Butyl-1H-pyrazole-3-carboxylic acid
Purity: ≥98% (HPLC)
Biological Activity for LUF 6283
LUF 6283 is a partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki = 0.55 μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
Technical Data for LUF 6283
| M. Wt | 168.19 |
| Formula | C8H12N2O2 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 92933-48-7 |
| PubChem ID | 6485181 |
| InChI Key | ZJTXSGLJNBAMJS-UHFFFAOYSA-N |
| Smiles | CCCCC1=CC(C(O)=O)=NN1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for LUF 6283
References for LUF 6283
References are publications that support the biological activity of the product.
Li et al (2012) Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice. Br.J.Pharmacol. 167 818 PMID: 22616721
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Keywords: LUF 6283, LUF 6283 supplier, LUF6283, HCA2, hydroxycarboxylic, acid, receptors, GPR109A, HM74A, partial, agonists, Hydroxycarboxylic, Acid, Receptors, 4881, Tocris Bioscience
Citations for LUF 6283
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