Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMN 64
Description: Potent and selective tankyrase inhibitor
Chemical Name: 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one
Purity: ≥98% (HPLC)
Biological Activity for MN 64
Potent and selective tankyrase (TNKS) inhibitor (IC50 values are 6 and 72 nM for TNKS1 and TNKS2 respectively). Has no significant effect on PARP-1 or PARP-2 (IC50 >19 μM). Inhibits WNT/β-catenin signaling-dependent Super-TopFlash (STF) luciferase activity.
Technical Data for MN 64
| M. Wt | 264.32 |
| Formula | C18H16O2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 92831-11-3 |
| PubChem ID | 2802462 |
| InChI Key | PYTOHIUBXSJKQH-UHFFFAOYSA-N |
| Smiles | O=C2C1=CC=CC=C1OC(C3=CC=C(C(C)C)C=C3)=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MN 64
References for MN 64
References are publications that support the biological activity of the product.
Narwal et al (2013) Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem. 56 7880 PMID: 24116873
View Related Products by Target
View Related Products by Product Action
Keywords: MN 64, MN 64 supplier, MN64, potent, selective, tankyrase, inhibitors, TNKS, TNKS1, TNKS2, WNT, inhibits, Poly(ADP-ribose), Polymerase, Tankyrase, 5084, Tocris Bioscience
Citations for MN 64
Citations are publications that use Tocris products.
Currently there are no citations for MN 64.
Reviews for MN 64
There are currently no reviews for this product. Be the first to review MN 64 and earn rewards!
Have you used MN 64?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
- Self-renewal and Maintenance
- Differentiation
- Reprogramming
- Organoid Generation
- GMP and Ancillary Material Grade Products