Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewBIM 189
Description: Bombesin antagonist
Alternative Names: [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2
Biological Activity for BIM 189
BIM 189 is a bombesin antagonist that reduces bombesin-induced satiety.
Technical Data for BIM 189
| M. Wt | 1137.73 |
| Formula | C56H73ClN14O10 |
| Sequence |
FQWAVGHLF (Modifications: Phe-1 = D-Phe, Phe-9 = 4-Cl-Phe & C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 142062-55-3 |
| PubChem ID | 5748499 |
| InChI Key | XJWMPWLZAVKSPK-UYBYNCNQSA-N |
| Smiles | [H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(Cl)C=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BIM 189
References for BIM 189
References are publications that support the biological activity of the product.
Coy et al (1990) Short chain bombesin pseudopeptides with potent bombesin receptor antagonist activity in rat and guinea pig acinar cells. Eur.J.Pharmacol. 190 31 PMID: 1963850
Laferrere et al (1992) Effects of bombesin, of a new bombesin agonist (BIM187) and a new antagonist (BIM189) on food intake in rats, in relation to cholecystokinin. Eur.J.Pharmacol. 215 23 PMID: 1516647
View Related Products by Target
View Related Products by Product Action
Keywords: BIM 189, BIM 189 supplier, Bombesin, antagonists, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, BIM189, [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2, 2717, Tocris Bioscience
Citations for BIM 189
Citations are publications that use Tocris products.
Currently there are no citations for BIM 189.
Reviews for BIM 189
There are currently no reviews for this product. Be the first to review BIM 189 and earn rewards!
Have you used BIM 189?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.