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Description: Induces cardiomyocyte differentiation from hESCs
Chemical Name: 4-(2-(2-Fluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Purity: ≥98% (HPLC)
Biological Activity for TA 02
Induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively).
Licensing Information
Sold under agreement from the Agency for Science, Technology and Research (A*STAR), ETPL, and affiliates including the Bioprocessing Technology Institute.
Technical Data for TA 02
| M. Wt | 333.33 |
| Formula | C20H13F2N3 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 91691130 |
| InChI Key | QIFJOFNVIVQRNJ-UHFFFAOYSA-N |
| Smiles | FC(C=C4)=CC=C4C(N=C(C3=C(F)C=CC=C3)N2)=C2C1=CC=NC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for TA 02
References for TA 02
References are publications that support the biological activity of the product.
Laco et al (2014) Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J.Mol.Cell.Cardiol PMID: 25528965
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Citations for TA 02
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