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Submit ReviewBiological Activity for pep4c
pep4c is an inactive control peptide analog of pep2m, a peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).
Active Analog also available.
Technical Data for pep4c
| M. Wt | 1146.42 |
| Formula | C48H91N17O13S |
| Sequence | KRMKVAKSAQ |
| Storage | Desiccate at -20°C |
| CAS Number | 243843-43-8 |
| PubChem ID | 90471151 |
| InChI Key | PUDVEKDEUNWDBZ-SKYKFSGJSA-N |
| Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for pep4c
References for pep4c
References are publications that support the biological activity of the product.
Collingridge and Isaac (2003) Functional roles of protein interactions with AMPA and kainate receptors. Neurosci.Res. 47 3 PMID: 12941441
Luscher et al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649 PMID: 10595516
Luthi et al (1999) Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron 24 389 PMID: 10571232
Nishimune et al (1998) NSF binding to GluR2 regulates synaptic transmission. Neuron 21 87 PMID: 9697854
Noel et al (1999) Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron 23 365 PMID: 10399941
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Keywords: pep4c, pep4c supplier, Inactive, control, peptide, 1595, Glutamate, AMPA, Receptors, iGlu, Ionotropic, GluR4cr, 1596, Tocris Bioscience
Citations for pep4c
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