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Submit ReviewNeuropeptide SF (human)
Description: Implicated in pain modulation and opioid function
Alternative Names: Neuropeptide NPFF (human FMRFamide-related)
Biological Activity for Neuropeptide SF (human)
Endogenous antiopioid peptide, implicated in pain modulation and endocrine functions. Potently activates the orphan G-protein-coupled receptor HLWAR77 (NPFF2) (EC50 = 0.39 nM).
Technical Data for Neuropeptide SF (human)
| M. Wt | 1367.57 |
| Formula | C65H94N18O15 |
| Sequence |
SQAFLFQPQRF (Modifications: Phe-11 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 192387-39-6 |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Neuropeptide SF (human)
References for Neuropeptide SF (human)
References are publications that support the biological activity of the product.
Elshourbagy et al (2000) Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J.Biol.Chem. 275 25965 PMID: 10851242
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Citations for Neuropeptide SF (human)
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Currently there are no citations for Neuropeptide SF (human).
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