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Submit ReviewNeurotensin
Description: Endogenous neurotransmitter and endocrine modulator
Purity: ≥95% (HPLC)
Biological Activity for Neurotensin
Neurotensin is a brain and gastrointestinal peptide with many central and peripheral functions. Acts as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally, acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular system.
Technical Data for Neurotensin
| M. Wt | 1672.94 |
| Formula | C78H121N21O20 |
| Sequence |
XLYENKPRRPYIL (Modifications: X = Glp) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 39379-15-2 |
| PubChem ID | 90488724 |
| InChI Key | PCJGZPGTCUMMOT-IMEZQUPBSA-N |
| Smiles | CC[C@@H](C)[C@@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Neurotensin
| Solubility | Soluble to 0.70 mg/ml in water |
Product Datasheets for Neurotensin
References for Neurotensin
References are publications that support the biological activity of the product.
Binder et al (2001) Neurotensin and DA interactions. Pharmacol.Rev. 53 453 PMID: 11734615
Tyler-McMahon (2000) Neurotensin: peptide for the next millenium. Regul.Pept. 93 125 PMID: 11033059
Vincent et al (1999) Neurotensin and neurotensin receptors. TiPS 20 302 PMID: 10390649
If you know of a relevant reference for Neurotensin, please let us know.
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Keywords: Neurotensin, Neurotensin supplier, Endogenous, neurotransmitter, endocrine, modulators, NT, Receptors, Neurotensin, agonists, 1909, Tocris Bioscience
Citations for Neurotensin
Citations are publications that use Tocris products.
Currently there are no citations for Neurotensin. Do you know of a great paper that uses Neurotensin from Tocris? Please let us know.
Reviews for Neurotensin
Average Rating: 5 (Based on 1 Review.)
Have you used Neurotensin?
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Neurotensin binding saturation and competition assays performed: Gives great publishable result.
By
Anonymous on 02/04/2019
Species: Human
Neurotensin binding Saturation Assay and a neurotensin binding Competition Assay were performed using the product. VICTOR™ Multi-label Reader has been used to measure the time-resolved fluorescence of each assay. The product gives great publishable results.
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.