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Submit ReviewAtrial natriuretic factor (1-28) (rat)
Description: Endogenous peptide regulating blood pressure
Alternative Names: Atrial Natriuretic Peptide (1-28) (rat)
Purity: ≥90% (HPLC)
Biological Activity for Atrial natriuretic factor (1-28) (rat)
Atrial natriuretic factor (1-28) (rat) is an endogenous peptide produced by the heart; involved in blood pressure regulation. Produces natriuresis, diuresis and vasorelaxation in vivo.
Technical Data for Atrial natriuretic factor (1-28) (rat)
| M. Wt | 3062.43 |
| Formula | C128H205N45O39S2 |
| Sequence |
SLRRSSCFGGRIDRIGAQSGLGCNSFRY (Modification: Disulfide bridge: 7-23) |
| Storage | Store at -20°C |
| Purity | ≥90% (HPLC) |
| CAS Number | 88898-17-3 |
| PubChem ID | 16166338 |
| InChI Key | QGFSVPWZEPKNDV-BRTFOEFASA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Atrial natriuretic factor (1-28) (rat)
| Solubility | Soluble to 1 mg/ml in water |
Product Datasheets for Atrial natriuretic factor (1-28) (rat)
References for Atrial natriuretic factor (1-28) (rat)
References are publications that support the biological activity of the product.
Atlas et al (1985) Atrial natriuretic factor (auriculin): structure and biological effects. J.Clin.Hypertens. 1 187 PMID: 2941526
de Bold et al (1985) Atrial natriuretic factor: a hormone produced by the heart. Science 230 767 PMID: 2932797
Rubattu and Volpe (2001) The atrial natriuretic peptide: a changing view. J.Hypertens. 19 1923 PMID: 11677356
If you know of a relevant reference for Atrial natriuretic factor (1-28) (rat), please let us know.
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Keywords: Atrial Natriuretic Factor (1-28) (rat), Atrial Natriuretic Factor (1-28) (rat) supplier, Endogenous, peptide, regulating, blood, pressure, ANP, Receptors, Atrial, Natriuretic, Peptide, NPR, (1-28), (rat), Receptor, 1912, Tocris Bioscience
Citations for Atrial natriuretic factor (1-28) (rat)
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NP in vitro.
By
Anonymous on 08/05/2018
Assay Type: In Vitro
Species: Rat
Used in vitro to investigate different roles of NP family members.