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Submit ReviewSecretin (human)
Description: Gastrointestinal peptide
Purity: ≥95% (HPLC)
Biological Activity for Secretin (human)
Secretin (human) is a gastrointestinal peptide that stimulates pancreatic and biliary secretion. Also thought to play a role in the regulation of the hypothalamus-pituitary-adrenal axis.
Secretin (rat) also available.
Technical Data for Secretin (human)
| M. Wt | 3039.44 |
| Formula | C130H220N44O40 |
| Sequence |
HSDGTFTSELSRLREGARLQRLLQGLV (Modifications: Val-27 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 108153-74-8 |
| PubChem ID | 16158474 |
| InChI Key | OWMZNFCDEHGFEP-NFBCVYDUSA-N |
| Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Secretin (human)
| Solubility | Soluble to 1 mg/ml in water |
Product Datasheets for Secretin (human)
References for Secretin (human)
References are publications that support the biological activity of the product.
Nussdorfer et al (2000) Secr., glucagon, gastric inhibitor polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus-pituitary-adrenal axis. Peptides 21 309 PMID: 10764961
Sherwood et al (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/Glucagon superfamily. Endocr.Rev. 21 619 PMID: 11133067
If you know of a relevant reference for Secretin (human), please let us know.
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Keywords: Secretin (human), Secretin (human) supplier, Gastrointestinal, peptide, Secretin, Receptors, Glucagon, 1918, Tocris Bioscience
1 Citation for Secretin (human)
Citations are publications that use Tocris products. Selected citations for Secretin (human) include:
Lee et al (2012) Secr. receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Mol Endocrinol 26 1394 PMID: 22692904
Do you know of a great paper that uses Secretin (human) from Tocris? Please let us know.
Reviews for Secretin (human)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.