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Submit ReviewIBC 293
Discontinued Product
2469 has been discontinued.
View all Hydroxycarboxylic Acid Receptors products.
Description: Selective agonist for the GPR109B (HM74) receptor. Antilipolytic
Chemical Name: 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid
Purity: ≥99% (HPLC)
Biological Activity for IBC 293
IBC 293 is a highly selective agonist for GPR109B (HM74), human orphan G-protein-coupled receptor expressed in adipocytes. Selective for GPR109B over niacin receptor GPR109A (HM74A); EC50 values are 400 nM and > 1 μM respectively. Inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes.
Technical Data for IBC 293
| M. Wt | 205.22 |
| Formula | C10H11N3O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 306935-41-1 |
| PubChem ID | 2736690 |
| InChI Key | RUTVRAJKELSHCC-UHFFFAOYSA-N |
| Smiles | CC(C)N1N=NC2=CC(=CC=C12)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for IBC 293
References for IBC 293
References are publications that support the biological activity of the product.
Semple et al (2006) 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b. J.Med.Chem. 49 1227 PMID: 16480258
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Keywords: IBC 293, IBC 293 supplier, Selective, agonists, GPR109B, HM74, receptors, Antilipolytic, GPR109, Receptors, Nicotinic, Acid, IBC293, Hydroxycarboxylic, 2469, Tocris Bioscience
Citations for IBC 293
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Currently there are no citations for IBC 293.
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