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Submit ReviewNaproxen sodium
Description: Cyclooxygenase inhibitor
Chemical Name: (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt
Purity: ≥99% (HPLC)
Biological Activity for Naproxen sodium
Naproxen sodium is a non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Technical Data for Naproxen sodium
| M. Wt | 252.24 |
| Formula | C14H13NaO3 |
| Storage | Desiccate at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 26159-34-2 |
| PubChem ID | 23681059 |
| InChI Key | CDBRNDSHEYLDJV-FVGYRXGTSA-M |
| Smiles | [Na+].COC1=CC=C2C=C(C=CC2=C1)[C@H](C)C([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Naproxen sodium
References for Naproxen sodium
References are publications that support the biological activity of the product.
Sutton (1996) Naproxen sodium. J.Am.Pharm.Assoc. (Wash) NS36 633 PMID: 8952250
Dhir et al (2006) Protective effect of naproxen (non-selective COX-inhibitor) or rofe. (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. Eur.J.Pharmacol. 535 192 PMID: 16522321
Kumar et al (2006) Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. Eur.J.Pharmacol. 551 58 PMID: 17027965
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Keywords: Naproxen sodium, Naproxen sodium supplier, Cyclooxygenase, inhibitors, inhibits, COX, Oxygenases, Oxidases, oxidative, stress, 2655, Tocris Bioscience
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