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Submit Review8-Aminoadenine
说明： Adenine receptor agonist
化学名： 9H-Purine-6,8-diamine
纯度： ≥98% (HPLC)
生物活性 for 8-Aminoadenine
8-Aminoadenine is an adenine receptor agonist (Ki = 0.0341 μM in HEK293 cells expressing an adenine binding site). Displays 190-fold increased potency at the human binding site over the rat adenine receptor (rAde1R) (Ki = 6.51 μM).
技术数据 for 8-Aminoadenine
| 分子量 | 150.14 |
| 公式 | C5H6N6 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 28128-33-8 |
| PubChem ID | 4371597 |
| InChI Key | PFUVOLUPRFCPMN-UHFFFAOYSA-N |
| Smiles | NC2=NC1=NC=NC(N)=C1N2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 8-Aminoadenine
参考文献 for 8-Aminoadenine
参考文献是支持产品生物活性的出版物。
Borrmann et al (2009) Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J.Med.Chem. 52 5974 PMID: 19731917
Bender et al (2002) Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc.Natl.Acad.Sci. 99 8573
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关键词: 8-Aminoadenine, 8-Aminoadenine supplier, p0, adenine, receptors, agonists, purinergic, signaling, signalling, Adenine, Receptor, 4050, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.