SMCy 5.5

Discontinued Product

7295 has been discontinued.

View all Fluorescent Lipid Probes and Cell Membrane Stains products.
说明: Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
化学名: 6,8-Dicyclohexyl-4-((1E,3E,5E)-5-(1,1-dimethyl-3-(pent-4-yn-1-yl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-2,2-difluoro-2,8-dihydro-5H-1λ3,2λ4-[1,3,2]dioxaborinino[6,5-d]pyrimidine-5,7(6H)-dione
纯度: ≥95% (HPLC)
说明书
引用文献
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文献 (1)

生物活性 for SMCy 5.5

Key information: SMCy 5.5 is a fluorogenic fluorescent probe for imaging lipid droplets. Supplied with an alkyne reactive handle for click chemistry. Suitable for deep tissue imaging and 3D imaging.

Application: Suitable for 2-photon excitation (2-PE) microscopy. Alkyne handle allows optional functionalization.

Properties and Photophysical Data: SMCy 5.5 exhibits sharp excitation and emission bands and high brightness. It displays high two-photon absorption (TPA) cross-section values (13330 GM and 10400 GM at 770 and 820 nm, respectively). Excitation and emission maxima (λ) for SMCy 5.5 in Tetrahydrofuran are 643nm and 672 nm, respectively; quantum yield = 0.75; extinction coefficient = 209,000 M-1 cm-1.

Optical Data for SMCy 5.5

SMCy 5.5 Dye Spectra
Emission Color Far Red
Brightness
λabs 636 nm
λem 660 nm
Extinction Coefficient (ε) 194,000 M-1cm-1
Quantum Yield (φ) 1
Closest Laser line 640 nm
Reactive Group Alkyne
Reactivity Click
Cell Permeable Yes
Application 2PE Fluorescence Imaging, Deep Tissue Imaging, 3D Imaging

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技术数据 for SMCy 5.5

分子量 693.64
公式 C41H46BF2N3O4
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2417507-09-4
InChI Key CCEAGIQCUXUBGY-GNVKXZRTSA-N
Smiles CC1(/C(N(C2=C1C3=CC=CC=C3C=C2)CCCC#C)=C\C=C\C=C\C4=C(C(N(C(N5C6CCCCC6)=O)C7CCCCC7)=O)C5=[O+][B-](F)(F)O4)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for SMCy 5.5

参考文献是支持产品生物活性的出版物。

Collot et al (2018) Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues. J.Am.Chem.Soc. 140 5401 PMID: 29446627

Fam et al (2018) Recent advances in fluorescent probes for lipid droplets. Materials (Basel) 11 1768 PMID: 30231571

关键词: SMCy 5.5, SMCy 5.5 supplier, Fluorescent, fluorogenic, probe, imaging, lipid, droplets, two-photon, microscopy, 2-photon, Lipid, Probes, and, Cell, Membrane, Stains, 7295, Tocris Bioscience

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals