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Submit ReviewXenin 8
说明： Neurotensin-like peptide; potentiates insulin and glucagon secretion
别名： Xenopsin-related peptide 1,XP-1
生物活性 for Xenin 8
Xenin 8 is a C-Terminal fragment of xenin, a neurotensin-like peptide; modulates pancreatic insulin and glucagon secretion/effects. Stimulates basal and arginine-induced insulin secretion and potentiates the insulin response to glucose (EC50 = 0.16 nM). Also potentiates arginine- and carbachol-induced glucagon secretion in a somatostatin-independent manner.
技术数据 for Xenin 8
| 分子量 | 1046.28 |
| 公式 | C51H79N15O9 |
| 序列 | HPKRPWIL |
| 储存 | Desiccate at -20°C |
| CAS Number | 117442-28-1 |
| PubChem ID | 90488740 |
| InChI Key | QNDRYLNMRDPBTI-OBOKMFOZSA-N |
| Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Xenin 8
参考文献 for Xenin 8
参考文献是支持产品生物活性的出版物。
Carraway et al (1988) Xenopsin-related peptide generated in avian gastric extracts. Regul.Pept. 22 303 PMID: 2460902
Feurle et al (2003) Metabolism and potency of xenin and of its reduced hexapseudopeptide ψ fragment in dog. Life Sci. 74 697 PMID: 14654163
Silvestre et al (2003) Stimulatory effect of xenin-8 on Ins and glucagon secretion in the perfused rat pancreas. Regul.Pept. 115 25 PMID: 12873795
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关键词: Xenin 8, Xenin 8 supplier, Neurotensin-like, peptide, potentiates, insulin, glucagon, secretion, NT, Receptors, Xenin8, Xenopsin, related, peptide1, Xenopsin-related, 1, XP-1, Neurotensin, 2138, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.