1R,3R-RSL3

Pricing Availability   Qty
说明: Negative control for 1S,3R-RSL3 (Cat. No. 6118)
化学名: (1R,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
纯度: ≥98% (HPLC)
说明书
引用文献
评论

生物活性 for 1R,3R-RSL3

1R,3R-RSL3 is a negative control for 1S,3R-RSL3 (Cat. No. 6118).

许可信息

Sold with the permission of Columbia University.

技术数据 for 1R,3R-RSL3

分子量 440.88
公式 C23H21ClN2O5
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1219810-15-7
PubChem ID 1750827
InChI Key TXJZRSRTYPUYRW-WIYYLYMNSA-N
Smiles COC([C@H]1CC2=C([C@@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=CC=CC=C24)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 1R,3R-RSL3

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 44.09 100

制备储备液 for 1R,3R-RSL3

以下数据基于产品分子量 440.88。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.27 mL 11.34 mL 22.68 mL
5 mM 0.45 mL 2.27 mL 4.54 mL
10 mM 0.23 mL 1.13 mL 2.27 mL
50 mM 0.05 mL 0.23 mL 0.45 mL

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参考文献 for 1R,3R-RSL3

参考文献是支持产品生物活性的出版物。

Yang et al (2016) Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc.Natl.Acad.Sci.U.S.A. 113 E4966 PMID: 27506793


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关键词: 1R,3R-RSL3, 1R,3R-RSL3 supplier, Ferroptosis, glutathione, peroxidase, 4, GPX4, inhibitors, inhibits, negative, controls, Other, Reductase, 6687, Tocris Bioscience

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